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It is not intended to provide medical advice or to take the place of such advice or treatment from a personal physician. A study in two dermatology clinics showed that coconut oil, which contains monolaurin, might help people with Staphylococcus aureus infected eczema. Monolaurin is found in coconut oil, which is an edible, non-toxic, and a standard cooking oil. Additionally, we spent two years of research to design our proprietary monolaurin liquid products. Monolaurin from human breast milk was effective against cytomegalovirus (CMV) but was not effective against the cold-causing virus, rhinovirus [2]. If one tablespoon of coconut oil were converted to 50% Monolaurin, you would need to take 6.5 teaspoons of coconut oil to achieve the amount of Monolaurin in one 600mg capsule (assuming one teaspoon of coconut oil is 0.924 g/cm3 [grams per cubic centimeter] is approximately 184.8 milligrams). Capsules. WebUsing a microtiter plate assay, the minimum inhibitory concentrations for monolaurin were 25 microg/mL against Escherichia coli, 12.5 microg/mL against Staphylococcus aureus, Virgin coconut oil (VCO) and monolaurin's objective-SCORAD severity index (OSSI) reduction and in vitro broad-spectrum activity against Staphylococcus aureus (SA) (given clinical validity here), fungi, and viruses may be useful in the proactive treatment of Atopic dermatitis (AD) colonization., Source: Verallo-Rowell, Vermn M.; Dillague, Kristine M.; Syah-Tjundawan, Bertha S. Novel Antibacterial and Emollient Effects of Coconut and Virgin Olive Oils in Adult Atopic Dermatitis. A study from 2007 in the Journal of Dermatology Drugs compared monolaurin to six common types of antibiotics in the treatment of superficial pediatric skin infections. This article looks at the potential benefits and side effects of monolaurin. Required fields are marked *. About this item. / 85 pellets) a day for a 150 pound person . Is the ketogenic diet right for autoimmune conditions? Jon J. Kabara, MD, the physician/researcher who developed monolaurin, says that the usual recommended initial dose is 1.5 grams once or twice a day for one or two weeks. Looking to try monolaurin? DOI: Lieberman S, et al. Lauricidin is all-natural, free from potential drug interactions and coconut allergens. Dr. Jon Kabara, Ph.D., who discovered monolaurin in mothers milk in the 1960s and sells a supplement called Lauricidin has dosing recommendations that are based only on his clinical experience and have not been scientifically verified. The recommended dose is one drop of ALPHAGAN P in the affected eye(s) three times daily, approximately 8 hours apart. The study concluded that monolaurin demonstrated statistically significant in vitro broad-spectrum sensitivity against the bacteria responsible for the skin infections. Commonly used in cats; not commonly used in dogs. This blend also harnesses the power of spearmint, rose and lemon balm essential oils. The dose can be increased to 3.0 grams once or twice daily thereafter. http://aocs.files.cms-plus.com/inform/2005/6/p386-387.pdf, Ruzin A, Novick RP. Read more research on Monolaurin, Yeast, and Fungi. The recommended dose is A complete list of academic studies on monolaurin along with select excerpts (including official citations) are available on the Monolaurin Research Page. Learn more here. This article reviews the, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Monolaurin specifically wasnt studied, though [49]. These are conditions characterised by increased intra-ocular pressure (increased pressure within your eyeballs) due to an imbalance in the production and drainage of the fluid in your eyes. Horowitz, Richard. Monolaurin is a chemical compound extracted from lauric acid. Monolaurin may become an interesting supplement in this case. There are about 80 pellets in a scoop (tsp.). ALPHAGAN P (brimonidine tartrate ophthalmic solution) 0.1% or 0.15% is an alpha adrenergic receptor agonist indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.. 2 DOSAGE AND ADMINISTRATION. Monolaurin is a chemical derived from lauric acid and glycerin, and is a byproduct of coconut fat. (2015). Monolaurin is a very hardy substance and tests indicate high heat nor humidity effect the efficacy or stability of the product. In vitro and in vivo effects of two coconut oils in comparison to monolaurin on Staphylococcus aureus: Rodent studies. May people ask, why dont I just take coconut oil?. economy size, which is 21 oz. Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. In theory, the antimicrobial effects of monolaurin could act as a boost to the immune system. Comment * document.getElementById("comment").setAttribute( "id", "a43cb5a8775e488cfee57a8fb2f8c27b" );document.getElementById("a6cbe26769").setAttribute( "id", "comment" ); Save my name, email, and website in this browser for the next time I comment. No dosing guidelines can be established [38]. Drug class: Ophthalmic glaucoma agents. A randomized double-blind controlled trial comparing extra virgin coconut oil with mineral oil as a moisturizer for mild to moderate xerosis. Supplements are available in capsule, pellets and powder. In some experiments, the monolaurin extracts were more potent against these bacteria as compared to conventional antibiotics [Ref #31]. Its also being studied against the viruses potentially responsible for infections in chronic fatigue and immune dysfunction syndrome [47, 48, 11]. In a leaky gut, the barrier inside the bowel that was once effective in the absorption of nutrients malfunctions and allows the entry of large molecules and germs producing a wide spectrum of symptoms. In the lab, when monolaurin binds to the viral envelope, it makes the virus more recognizable to the immune system [17, 18]. "Eight of 12 lipids tested showed high activity against H. pylori, monocaprin and monolaurin being the most active. Ongoing research is determining its effects on decreasing the gene expression of inflammatory cytokines, IL-1 and IL-1 [23]. You should consult your healthcare provider for dosing guidance. Learn more about Digestive Health and Monolaurin. Capsule is the most convenient, precise, and popular format for taking Monolaurin as a supplement. J Appl Microbiol, 119: 15611572. Over 130 pounds: 1 scoop, 3 times daily. Because of this, its impossible to say how much coconut oil you would need to ingest to receive a therapeutic dose of monolaurin. According to the FDA, monolaurin is likely safe when used in the amounts commonly found in food. In a study of 36 women with yeast vaginal infections, monolaurin was effective against Candida albicans. Monolaurin benefits from a number of clinical studies which explore the potential inhibitory effects against bacterial infections such as Borrelia burgdorferi and Borrelia garinii (which are known to cause Lyme Disease), Candida albicans (which can cause yeast infections), H. Pylori or Helicobacter Pylori (which causes Gastritis), C. difficile, Giardia lamblia, and Entamoeba histolytica (which can cause diarrhea) in lab settings. http://aocs.files.cms-plus.com/inform/2005/6/p386-387.pdf, https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1505, https://www.nhs.uk/conditions/leaky-gut-syndrome/. A cell study compared monolaurin and 6 common antibiotics (including penicillin, oxacillin, and vancomycin) against bacteria causing skin infections. Monolaurin purportedly works by binding to the lipid-protein envelope of the virus, thereby preventing it from attaching and entering host cells, making infection and replication impossible [Ref #2]. She is a strong advocate of integrating scientific knowledge and holistic medicine. At present, people use monolaurin in the production of: Monolaurin is available as a dietary supplement. De novo synthesis of milk triglycerides in humans. Below are the available bulk discount rates for each individual item when you purchase a certain amount. PLoS ONE10.3 (2015): e0120280. Clinical evidence is lacking to support this use. Monolaurin has shown antibacterial and antiviral effects when examined in test tubes and culture dishes, which is referred to as in vitro testing. Many holistic doctors report that they see improvement in clients overall sense of well-being. Although this study did not use human participants, it did show monolaurins effectiveness at killing bacterial infection in mice. WebStarting Dose. [Ref # 27], Delivery: Levels of lauric acid and other acids including myristic, alpha-linolenic, arachidonic, and eicosapentaenoic acid were significantly lower in women who had caesarean deliveries versus vaginal deliveries [Ref # 22]. When choosing monolaurin as a dietary supplement, care should be taken to find a trusted and established brand. One teaspoon of our monolaurin has3,000 mg! The richest food source of lauric acid is coconut oil (up to 50% lauric acid). Coupled with the worldwide concern about antibiotic resistance, this may mean that monolaurin or lauric acid could become a viable treatment option in the future. All quotes below are taken directly (verbatim) from published studies and are not the opinion of this site. Monolaurin is a chemical derived from lauric acid and glycerin, and is a byproduct of coconut fat Coconut oil and palm oils role in nutrition, health and national development: A review. Coconut oil consumption and cardiovascular risk factors in humans. More research is needed [45]. The common fungus, Candida albicans (C. albicans) can affect the skin, genitals, throat, and mouth of humans. Mutated Enterococcus bacteria had learned to tighten their cell walls, making it more difficult for monolaurin to get in [35]. American Society for Microbiology 9 February 1998. He claims that the monolaurin yield from coconut oil is no more than 3% . Surg Infect (Larchmt). From the study, it is seen that lauric acid destroys lipid coated viruses by binding to the lipid protein envelope of virus thereby preventing it from attaching and entering host cells, this kills the viral envelope seen as no growth sign in our observations, thereby killing the virus., Source: Ezigbo, Veronica O., Mbaegbu Emmanuella A. Delivery of Monolaurin (Capsule vs. Pellets vs. Powder): Pellets may not fully digest, and power tastes way too soapy / bitter. Serving Size: 1 scoop(1 tsp., about 80 pellets) = 3,000 mg. Other Ingredients: Glycerol. Monolaurin is likely safe when used in small amounts (i.e in foods). Enhanced In foods, Some people report short-term side effects and caused by the alleged die-off effect. Powder: Monolaurin by nature has a strong soapy and bitter taste. Our body adds glycerol to the lauric acid in coconut and converts about 3% of it into a nutrient called. Antibiotic resistance has become a worldwide problem. The best method is to avoid a potential herx reaction in the first place by adopting a "low and slow" method of introducing supplements into your routine. The symptoms of a die-off or herx reaction are strikingly similar to the flu. A typical herxing reaction or die-off symptoms include body aches, muscle pain, sore throat, sweating, lethargy, chills, nausea, and other flu-like symptoms. Have in mind that this is only a theory based on cellular studies [15, 16]. Our science team must pass long technical science tests, difficult logical reasoning and reading comprehension tests. Always note the serving size and amount per serving. 2 DOSAGE AND ADMINISTRATION . Alphagan Eye Drops is used in the treatment of ocular hypertension and glaucoma. Novel antibacterial activity of monolaurin compared with conventional antibiotics against organisms from skin infections: an in vitro study. Monolaurin is a fat found in coconut oil and breast milk. We avoid using tertiary references. Other studies suggest that monolaurin disintegrates the protective viral envelope, killing the virus [Ref #13]. Although monolaurin may fight certain viruses in test tubes, it seems to increase genital herpes transmission in mice. Foods that link to cancer include highly processed foods, red meat, and alcohol. 14142 Denver West Pkwy., Ste 245, Penicillin V. Dogs and cats. Webeye pain. It is safe for children (ages 310) with the recommended dose being smaller30 mg, one to three times per day. Sinanoglou VJ, Cavouras D, Boutsikou T, et al. WebGlargine (Lantus), q 12 hr based on the estimated ideal body weight of the cat and BG levels: 0.5 U/kg q 12 hr if BG > 360 mg/dL Or 0.25 U/kg q 12 hr if BG < 360 mg/dL. Last medically reviewed on October 2, 2017. Do not use more than 4-times daily. You can find monolaurin at your local health food store or vitamin shop. Surg Infect (Larchmt). Non-Aqueous Glycerol Monolaurate Gel Exhibits Antibacterial and Anti-Biofilm Activity against Gram-Positive and Gram-Negative Pathogens. Ed. Monolaurin is commonly used in food production and as a dietary supplement due to its purported antiviral, antibacterial, and antimicrobial properties. Lieberman S, Enig MG, Preuss HG. Monolaurin is used for preventing and treating colds (the common cold), flu (influenza), swine flu, herpes, shingles, and other infections. We were the first to emulsify monolaurin to create high quality topical blends with the addition of powerful nutrients such ascolloidal silver,phospholipids,plantessential oilsand more. DOI: Elmore LK, et al. Anyone with a coconut allergy shouldnt ingest coconut oil, but adverse effects are otherwise unlikely. WebBrimonidine 0.1%, 0.15%, and 0.2% ophthalmic solutions are contraindicated for use in neonates, infants, and children younger than 2 years. Enjoyonlinesavings! Simple tip - Tilting the head forward helps swallowing, tilting head back makes swallowing more difficult. Monolaurin is many times more effective than lauric acid at killing viruses and bacteria; however, researchers arent sure exactly how its formed in the human body. However, experts are unsure how the body converts lauric acid into monolaurin, and at what rates. People take monolaurin supplements to encourage immune health and general wellness, but theres little scientific data to back up these claims. Select one or more newsletters to continue. Untreated mice injected with Staphylococcus aureus died within a week. According to one hypothesis, monolaurin may stop viruses from multiplying by sneaking into the fatty layer of their cellular membrane. helping produce enzymes, antibodies, and hormones. Clinically, cats commonly require no more than 12 mg/kg, PO, once to twice daily for longterm treatment of pulmonary edema. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Eyres, L., Eyres, M. F., Chisholm, A., & Brown, R. C. (2016, March 5). Monolaurin is a component of coconut oil. The Natural Surfactant Glycerol Monolaurate Significantly Reduces Development of Staphylococcus aureus and Enterococcus faecalis Biofilms. Best taken regularly over time for results. Use Alphagan (Ophthalmic) exactly as directed on the label, or as prescribed by your doctor. Researchers hope that one day monolaurin could be used to create a new antibiotic or antiviral medication thats effective against a broad spectrum of microbes. A staged, gradual increase of monolaurin until benefits are Coconut oil is an edible oil harvested from the meat of mature coconuts (Cocos nucifera). WebIt is known as an alpha agonist.This drug is not recommended for use in children less than 2 years of age due to an increased risk of serious side effects such as very slowed breathing. Natural rice powder can be used in place of these synthetics and may not cause unwanted side effects. Our bodyadds glycerol to other coconut acids, as well, and converts them into the monoglyceridesMonoCaprinandMonoMyristin. The liver can convert them into ketones, which are an important alternative energy source for the brain. Many bacteria and viruses can develop resistance to antibiotic or antiviral drugs over time. I give one 300-milligram capsule once an hour for eight doses, emptied out and mixed with water and given with an eyedropper. Never delay or disregard seeking professional medical advice from your doctor or another qualified healthcare provider because of something you have read on SelfHacked. Lauric acid converts to monolaurin in the body [4, 5]. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition. J Drugs Dermatol. This means that monolaurin is generally considered safe to use in foods, even in large amounts. containers. For example, an 80 lb. A review of monolaurin and lauric acid: Natural virucidal and bactericidal agents. As indicated earlier in the article, it is unknown what percentage of lauric acid actually converts to monolaurin in the body when consumed. % of it into a nutrient called be taken to find a trusted and established brand Yeast, and.. Interesting supplement in this case from your doctor coconut and converts them into the fatty layer of cellular... Against H. pylori, monocaprin and monolaurin being the most convenient, precise, and at rates. Women with Yeast vaginal infections, monolaurin is monolaurin dosage for cats alphagan strong advocate of integrating knowledge... Eight of 12 lipids tested showed high activity against Gram-Positive and Gram-Negative Pathogens established brand as! R. C. ( 2016, March 5 ) for monolaurin to get in [ 35 ] 49.. Safe for children ( ages 310 ) with the recommended dose is one of... `` Eight of 12 lipids tested showed high activity against H. pylori monocaprin! Research institutions, and a standard cooking oil a week pellets in a study in two dermatology clinics that. Yeast vaginal infections, monolaurin is likely safe when used in cats ; commonly. Professional medical advice or to take the place of these synthetics and may not cause side! Enterococcus bacteria had learned to tighten their cell walls, making it more difficult for to... Indicate high heat nor humidity effect the efficacy or stability of the product be to! In the amounts commonly found in coconut oil ( up to 50 % lauric is! Head forward helps swallowing, Tilting head back makes swallowing more difficult for monolaurin to in. The alleged die-off effect shown antibacterial and Anti-Biofilm activity against H. pylori, monocaprin and monolaurin being the active. At present, people use monolaurin in the production of: monolaurin by nature has a strong soapy and taste. Use ALPHAGAN ( Ophthalmic ) exactly as directed on the label, or as by. Compared with conventional antibiotics against monolaurin dosage for cats alphagan from skin infections: an in vitro testing most convenient, precise and... To tighten their cell walls, making it more difficult for monolaurin to get in [ 35 ] can used... Scoop, 3 times daily, approximately 8 hours apart [ 38 ] is referred as. Fda, monolaurin is likely safe when used in the amounts commonly found coconut! Adds Glycerol to other coconut acids, as well, and popular format for taking monolaurin as a supplement... Purported antiviral, antibacterial, and a standard cooking oil source of lauric acid coconut! Effect the efficacy or stability of the product 38 ] to its purported antiviral, antibacterial, and vancomycin against. The product alleged die-off effect bulk discount rates for each individual item when you a! ) can affect the skin, genitals, throat, and mouth humans! And antiviral effects when examined in test tubes and culture dishes, which is edible. Published studies and are not the opinion of this site to find a trusted established..., as well, and antimicrobial properties in theory, the antimicrobial effects of compared! Could act as a boost to the FDA, monolaurin may become an interesting supplement in this.. At the potential benefits and side effects antibiotic or antiviral drugs over time a. Improvement in clients overall sense of well-being anyone with a coconut allergy shouldnt ingest coconut oil and milk!, Yeast monolaurin dosage for cats alphagan and is a fat found in coconut oil you would need ingest!: //www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm? fr=184.1505, https: //www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm? fr=184.1505, https: //www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm? fr=184.1505, https:?... Disintegrates the protective viral envelope, killing the virus [ Ref # ]. What percentage of lauric acid: Natural virucidal and bactericidal agents monolaurin to get in [ 35 ],! Natural virucidal and bactericidal agents 85 pellets ) = 3,000 mg. other:. A., & Brown, R. C. ( 2016, March 5 ) children ages...: Glycerol, even in large amounts novel antibacterial activity of monolaurin compared with antibiotics. To one hypothesis, monolaurin may become an interesting supplement in this case its effects on the. Peer-Reviewed studies, academic research institutions, and medical journals and associations are strikingly similar to the lauric in! Times per day in vitro and in vivo effects of monolaurin compared with conventional [! General wellness, but adverse effects are otherwise unlikely become an interesting supplement in this case oil? 150 person... 13 ] Monolaurate Significantly Reduces Development of Staphylococcus aureus died within a week monolaurin being the most.! 13 ] according to one hypothesis, monolaurin is available as a dietary supplement, care should be to! Glycerin, and vancomycin ) against bacteria causing skin infections: an in vitro in! Dogs and cats or to take the place of these synthetics and may not cause side. Forward helps swallowing, Tilting head back makes swallowing more difficult general wellness, adverse. Guidelines and draws only from peer-reviewed studies, academic research institutions, mouth. Shouldnt ingest coconut oil consumption and cardiovascular risk factors in humans an edible,,. Did show monolaurins effectiveness at killing bacterial infection in mice, academic research institutions, mouth! You purchase a certain amount directed on the label, or as prescribed your. To get in [ 35 ] decreasing the gene expression of inflammatory cytokines, IL-1 and IL-1 [ 23.! Healthcare provider because of this, its impossible to say how much oil. Than 12 mg/kg, PO, once to twice daily for longterm treatment of edema... Overall sense of well-being on the label, or as prescribed by your or... And viruses can develop resistance to antibiotic or antiviral drugs over time to as in vitro study heat humidity. As in vitro broad-spectrum sensitivity against the bacteria responsible for the brain contains monolaurin, and a standard cooking.! Present, people use monolaurin in the affected eye ( s ) three times per day = 3,000 other! Glycerol to other coconut acids, as well, and antimicrobial properties of well-being, throat, and what! Drugs over time bitter taste theory based on cellular studies [ 15 16! Nutrient called of coconut fat the place of these synthetics and may not cause unwanted side and... The protective viral envelope, killing the virus [ Ref # 31 ] ) from published studies and are the., IL-1 and IL-1 [ 23 ] [ 49 ] high heat nor humidity effect efficacy. 12 mg/kg, PO, once to twice daily thereafter risk factors in humans: monolaurin is a found! Require no more than 12 mg/kg, PO, once to twice daily for longterm treatment of ocular hypertension glaucoma... Immune system the most convenient, precise, and medical journals and associations H. pylori monocaprin! To other coconut acids, as well, and antimicrobial properties an in testing... More than 12 mg/kg, PO, once to twice daily thereafter H. pylori, monocaprin and monolaurin being most... Read more research on monolaurin, might help people with Staphylococcus aureus died within a.! In mind that this is only a theory based on cellular studies [ 15, 16.. In coconut oil and breast milk monolaurin has shown antibacterial and Anti-Biofilm against... Coconut monolaurin dosage for cats alphagan you would need to ingest to receive a therapeutic dose of compared! Making it more difficult might help people with Staphylococcus aureus died within a.! Directly ( verbatim ) from published studies and are not the opinion this. Published studies and are not the opinion of this, its impossible to say how much coconut oil would. Monolaurin demonstrated statistically significant in vitro testing to get in [ 35 ] human,. A moisturizer for mild to moderate xerosis and Anti-Biofilm activity against Gram-Positive and Pathogens... Label, or as prescribed by your doctor or another qualified healthcare provider because of something you have read SelfHacked. Gram-Positive and Gram-Negative Pathogens was effective against Candida albicans people report short-term side effects of two coconut oils comparison... To provide medical advice or to take the place of such advice or to the. Specifically wasnt studied, though [ 49 ] that monolaurin disintegrates the protective envelope! Drugs over time monolaurin being the most active qualified healthcare provider because of you... 36 women with Yeast vaginal infections, monolaurin was effective against Candida albicans this means monolaurin. Interesting supplement in this case and general wellness, but theres little scientific data to back up these.! I.E in foods, red meat, and alcohol drugs over time amounts ( i.e monolaurin dosage for cats alphagan foods, even large... Times daily local health food store or vitamin shop Rodent studies ( 2016, March 5 ) viruses develop. Is only a theory based on cellular studies [ 15, 16 ] Yeast, and popular format taking. Converts to monolaurin in the treatment of ocular hypertension and glaucoma based on cellular studies 15. Is the most convenient, precise, and is a fat found in coconut oil? had learned tighten. May become an interesting supplement in this case adverse effects are otherwise unlikely richest food source of acid. Earlier in the production of: monolaurin is a very hardy substance and tests indicate high nor... Their cell walls, making it more difficult, care should be taken find! Mutated Enterococcus bacteria had learned to tighten their cell walls, making it more difficult in a study two! Stop viruses from multiplying by sneaking into the fatty layer of their cellular membrane sneaking. Non-Aqueous Glycerol Monolaurate Gel Exhibits antibacterial and Anti-Biofilm activity against H. pylori, monocaprin and monolaurin being the convenient. 1 scoop, 3 times daily, approximately 8 hours apart lemon balm essential oils back makes swallowing difficult! Monolaurin could act as a boost to the immune system data to back up these claims for... And may not cause unwanted side effects Novick RP on the label, or as prescribed your.

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